Mitochondrial outer membrane contains a protein producing nonspecific diffusion channels.
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منابع مشابه
Mitochondrial outer membrane contains a protein producing nonspecific diffusion channels.
Vesicles permeable to sucrose, but not to high molecular weight dextrans, were produced when fragments of mitochondrial outer membrane obtained from rat liver or mung bean seedlings were fused with liposomes of soybean phospholipids. By using this reconstitution assay, the channel-forming protein in the mung bean mitochondria was identified as protein(s) with an apparent molecular weight of 30,...
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The outer mitochondrial membrane protein mitoNEET was discovered as a binding target of pioglitazone, an insulin-sensitizing drug of the thiazolidinedione class used to treat type 2 diabetes (Colca, J. R., McDonald, W. G., Waldon, D. J., Leone, J. W., Lull, J. M., Bannow, C. A., Lund, E. T., and Mathews, W. R. (2004) Am. J. Physiol. 286, E252-E260). We have shown that mitoNEET is a member of a ...
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Received for publication, May 31, 2007, and in revised form, June 20, 2007 Published, JBC Papers in Press, June 21, 2007, DOI 10.1074/jbc.C700107200 Sandra E. Wiley, Mark L. Paddock, Edward C. Abresch, Larry Gross, Peter van der Geer , Rachel Nechushtai**, Anne N. Murphy, Patricia A. Jennings, and Jack E. Dixon From the Departments of Pharmacology, Physics, Chemistry and Biochemistry, and Cellu...
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Transport of molecules across mitochondrial outer membrane is pivotal for a proper function of mitochondria. The transport pathways across the membrane are formed by ion channels that participate in metabolite exchange between mitochondria and cytoplasm (voltage-dependent anion-selective channel, VDAC) as well as in import of proteins encoded by nuclear genes (Tom40 and Sam50/Tob55). VDAC, Tom4...
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The outer membrane of Pseudomonas aeruginosa PA01 is permeable to saccharides of molecular weights lower than about 6000. Triton X-100/EDTAsoluble outer membrane proteins were fractionated by ion-exchange chromatography in the presence of Triton X-100 and EDTA, and the protein contents of the various fractions analysed by sodium dodecyl sulphate polyacrylamide gel electrophoresis. Each of the m...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1980
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)85942-2